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A Quantitative Model of the Effect of Unreplicated DNA on Cell Cycle Progression in Frog Egg Extracts

A critical goal in cell biology is to develop a systems-level perspective of eukaryotic cell cycle controls. Among these controls, a complex signaling network (called ‘checkpoints’) arrests progression through the cell cycle when there is a threat to genomic integrity such as unreplicated or damaged...

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Autors principals: Zwolak, Jason, Adjerid, Nassiba, Bagci, Elife Z., Tyson, John J., Sible, Jill C.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763306/
https://ncbi.nlm.nih.gov/pubmed/19490919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2009.05.018
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