A NMDA Receptor Antagonist, MK-801 Impairs Consolidating Extinction of Auditory Conditioned Fear Responses in a Pavlovian Model

BACKGROUND: In auditory fear conditioning, repeated presentation of the tone in the absence of shock leads to extinction of the acquired fear responses. The glutamate N-methyl-D-aspartate receptor (NMDAR) is thought to be involved in the extinction of the conditioned fear responses, but its detailed...

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Main Authors: Liu, Jun-Li, Li, Min, Dang, Xiao-Rong, Wang, Zheng-Hong, Rao, Zhi-Ren, Wu, Sheng-Xi, Li, Yun-Qing, Wang, Wen
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763217/
https://ncbi.nlm.nih.gov/pubmed/19855841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007548
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