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Toxoplasma gondii Inhibits Covalent Modification of Histone H3 at the IL-10 Promoter in Infected Macrophages

Infection of macrophages with the protozoan parasite Toxoplasma gondii results in inhibition of a large panel of LPS-responsive cytokines, including TNF-α, while leaving others such as IL-10 intact. Recent studies provide evidence that the parasite interferes with chromatin remodeling at the TNF-α p...

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Detalhes bibliográficos
Main Authors: Leng, Jin, Denkers, Eric Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763200/
https://ncbi.nlm.nih.gov/pubmed/19859561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007589
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