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Human embryonic stem cell lines derived from single blastomeres of two 4-cell stage embryos

BACKGROUND: Recently, we demonstrated that single blastomeres of a 4-cell stage human embryo are able to develop into blastocysts with inner cell mass and trophectoderm. To further investigate potency at the 4-cell stage, we aimed to derive pluripotent human embryonic stem cells (hESC) from single b...

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Autors principals: Geens, Mieke, Mateizel, Ileana, Sermon, Karen, De Rycke, Martine, Spits, Claudia, Cauffman, Greet, Devroey, Paul, Tournaye, Herman, Liebaers, Inge, Van de Velde, Hilde
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763129/
https://ncbi.nlm.nih.gov/pubmed/19633307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/humrep/dep262
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