Bcl-2 and Bax Expression Predict Prostate Cancer Outcome in Men Treated with Androgen Deprivation and Radiotherapy on Radiation Therapy Oncology Group Protocol 92-02

PURPOSE: Bcl-2 is antiapoptotic, and its overexpression has been associated with resistance to androgen deprivation and poor outcome in some patients treated with radiotherapy. Bax is proapoptotic, regulating Bcl-2 through heterodimer formation. In a prior study, Bcl-2 and Bax were not related to ou...

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Hlavní autoři: Khor, Li Yan, Moughan, Jennifer, Al-Saleem, Tahseen, Hammond, Elizabeth H., Venkatesan, Varagur, Rosenthal, Seth A., Ritter, Mark A., Sandler, Howard M., Hanks, Gerald E., Shipley, William U., Pollack, Alan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763095/
https://ncbi.nlm.nih.gov/pubmed/17575222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-06-2972
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