[(11)C]-DPA-713 and [(18)F]-DPA-714 as New PET Tracers for TSPO: A Comparison with [(11)C]-(R)-PK11195 in a Rat Model of Herpes Encephalitis

BACKGROUND: Activation of microglia cells plays an important role in neurological diseases. Positron emission tomography (PET) with [(11)C]-(R)-PK11195 has already been used to visualize activated microglia cells in neurological diseases. However, [(11)C]-(R)-PK11195 may not possess the required sen...

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Bibliographic Details
Main Authors: Doorduin, Janine, Klein, Hans C., Dierckx, Rudi A., James, Michelle, Kassiou, Michael, de Vries, Erik F. J.
Format: Artigo
Language:Inglês
Published: Springer-Verlag 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763079/
https://ncbi.nlm.nih.gov/pubmed/19330384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-009-0211-6
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