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A trans-acting RNA as a control switch in Escherichia coli: DsrA modulates function by forming alternative structures

DsrA is an 87-nucleotide regulatory RNA of Escherichia coli that acts in trans by RNA–RNA interactions with two different mRNAs, hns and rpoS. DsrA has opposite effects on these transcriptional regulators. H-NS levels decrease, whereas RpoS (σ(s)) levels increase. Here we show that DsrA enhances hns...

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Bibliografski detalji
Glavni autori: Lease, Richard A., Belfort, Marlene
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2000
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC27626/
https://ncbi.nlm.nih.gov/pubmed/10954740
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