Notch-RBP-J Signaling Regulates the Mobilization and Function of Endothelial Progenitor Cells by Dynamic Modulation of CXCR4 Expression in Mice

Bone marrow (BM)-derived endothelial progenitor cells (EPC) have therapeutic potentials in promoting tissue regeneration, but how these cells are modulated in vivo has been elusive. Here, we report that RBP-J, the critical transcription factor mediating Notch signaling, modulates EPC through CXCR4....

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Main Authors: Wang, Lin, Wang, Yao-Chun, Hu, Xing-Bin, Zhang, Bing-Fang, Dou, Guo-Rui, He, Fei, Gao, Fang, Feng, Fan, Liang, Ying-Min, Dou, Ke-Feng, Han, Hua
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2009
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762521/
https://ncbi.nlm.nih.gov/pubmed/19859544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007572
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