Treatment of congenital fibrinogen deficiency: overview and recent findings

Afibrinogenemia is a rare bleeding disorder with an estimated prevalence of 1:1,000,000. It is an autosomal recessive disease resulting from mutations in any of the 3 genes that encode the 3 polypeptide chains of fibrinogen and are located on the long arm of chromosome 4. Spontaneous bleeding, bleed...

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Bibliographic Details
Main Authors: Tziomalos, Konstantinos, Vakalopoulou, Sofia, Perifanis, Vassilios, Garipidou, Vassilia
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2009
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762433/
https://ncbi.nlm.nih.gov/pubmed/19851522
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