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Membrane cholesterol is a biomechanical regulator of neutrophil adhesion

OBJECTIVE: To evaluate the role of membrane cholesterol on human neutrophil and HL-60 biomechanics, capture, rolling, and arrest to P-selectin or IL-1-activated endothelium. METHODS AND RESULTS: Methyl-β-cyclodextrin (MβCD) removed up to 73% and 45% of membrane cholesterol from HL-60 cells and neutr...

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Autors principals: Oh, Hana, Mohler, Emile R., Tian, Aiwei, Baumgart, Tobias, Diamond, Scott L.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762395/
https://ncbi.nlm.nih.gov/pubmed/19667108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.109.189571
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