Melanoma Proteoglycan Modifies Gene Expression to Stimulate Tumor Cell Motility, Growth and Epithelial to Mesenchymal Transition

Melanoma chondroitin sulfate proteoglycan (MCSP) is a plasma membrane-associated proteoglycan that facilitates the growth, motility and invasion of tumor cells. MCSP expression in melanoma cells enhances integrin function and constitutive activation of Erk 1,2. The current studies were performed to...

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Main Authors: Yang, Jianbo, Price, Matthew A., Li, GuiYuan, Bar-Eli, Menashe, Salgia, Ravi, Jagedeeswaran, Ramasamy, Carlson, Jennifer H., Ferrone, Soldano, Turley, Eva A., McCarthy, James B.
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762355/
https://ncbi.nlm.nih.gov/pubmed/19738072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-4626
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