DNA replication times the cell cycle and contributes to the mid-blastula transition in Drosophila embryos

We examined the contribution of S phase in timing cell cycle progression during Drosophila embryogenesis using an approach that deletes S phase rather than arresting its progress. Injection of Drosophila Geminin, an inhibitor of replication licensing, prevented subsequent replication so that the fol...

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Bibliographic Details
Main Authors: McCleland, Mark L., Shermoen, Antony W., O'Farrell, Patrick H.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2009
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762091/
https://ncbi.nlm.nih.gov/pubmed/19786576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200906191
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