Towards a systems biology approach to mammalian cell cycle: modeling the entrance into S phase of quiescent fibroblasts after serum stimulation

BACKGROUND: The cell cycle is a complex process that allows eukaryotic cells to replicate chromosomal DNA and partition it into two daughter cells. A relevant regulatory step is in the G(0)/G(1 )phase, a point called the restriction (R) point where intracellular and extracellular signals are monitor...

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Detalhes bibliográficos
Main Authors: Alfieri, Roberta, Barberis, Matteo, Chiaradonna, Ferdinando, Gaglio, Daniela, Milanesi, Luciano, Vanoni, Marco, Klipp, Edda, Alberghina, Lilia
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762065/
https://ncbi.nlm.nih.gov/pubmed/19828076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-10-S12-S16
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