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Effects of cascade length, kinetics, and feedback loops on biological signal transduction dynamics in a simplified cascade model
How intracellular signals are propagated with the appropriate strength, duration and fidelity over time is poorly understood. To address these issues, intracellular signal transduction was studied both analytically and numerically using a simplified cascade model. The main observations can be summar...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2761888/ https://ncbi.nlm.nih.gov/pubmed/19242047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1478-3975/6/1/016007 |
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