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Control of CD56 expression and tumor cell cytotoxicity in human Vγ2Vδ2 T cells

BACKGROUND: In lymphocyte subsets, expression of CD56 (neural cell adhesion molecule-1) correlates with cytotoxic effector activity. For cells bearing the Vγ2Vδ2 T cell receptor, isoprenoid pyrophosphate stimulation leads to uniform activation and proliferation, but only a fraction of cells express...

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Detalhes bibliográficos
Main Authors: Urban, Elizabeth M, Li, Haishan, Armstrong, Cheryl, Focaccetti, Chiara, Cairo, Cristiana, Pauza, C David
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761874/
https://ncbi.nlm.nih.gov/pubmed/19772585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-10-50
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