Regulatory activity of azabisphosphonate-capped dendrimers on human CD4(+ )T cell proliferation enhances ex-vivo expansion of NK cells from PBMCs for immunotherapy

BACKGROUND: Adoptive cell therapy with allogenic NK cells constitutes a promising approach for the treatment of certain malignancies. Such strategies are currently limited by the requirement of an efficient protocol for NK cell expansion. We have developed a method using synthetic nanosized phosphon...

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Autors principals: Portevin, Damien, Poupot, Mary, Rolland, Olivier, Turrin, Cédric-Olivier, Fournié, Jean-Jacques, Majoral, Jean-Pierre, Caminade, Anne-Marie, Poupot, Remy
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761872/
https://ncbi.nlm.nih.gov/pubmed/19778420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-7-82
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