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Multiple pathways in the FGF signaling network are frequently deregulated by gene amplification in oral dysplasias

Genetic alteration in oral premalignant lesions (OPLs), the precursors of oral squamous cell carcinomas (OSCCs), may represent key changes in disease initiation and development. We ask if DNA amplification occurs at this early stage of cancer development and which oncogenic pathways are disrupted in...

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Main Authors: Tsui, Ivy F.L., Poh, Catherine F., Garnis, Cathie, Rosin, Miriam P., Zhang, Lewei, Lam, Wan L.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761835/
https://ncbi.nlm.nih.gov/pubmed/19623652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.24611
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