Synergy of TRIF-dependent TLR3 and MyD88-dependent TLR7 in up-regulating expression of mouse FPR2, a promiscuous G-protein-coupled receptor, in microglial cells

Human G-protein-coupled formyl peptide receptor-like 1 and its mouse homologue formyl peptide receptor 2 mediate the chemotactic activity of a variety of pathogen and host-derived peptides, including amyloid β(42), a key causative factor in Alzheimer’s disease (AD). Here, we found that Polyinosine-p...

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Библиографические подробности
Главные авторы: Chen, Keqiang, Huang, Jian, Liu, Ying, Gong, Wanghua, Cui, Youhong, Wang, Ji Ming
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761824/
https://ncbi.nlm.nih.gov/pubmed/19559490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2009.05.018
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