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Stromal Edema in Klf4 Conditional Null Mouse Cornea is Associated with Altered Collagen Fibril Organization and Reduced Proteoglycans

PURPOSE: Klf4, one of the highly expressed transcription factors in mouse cornea, plays an important role in maturation and maintenance of the ocular surface. Here, the authors examined the structure and proteoglycan composition of the Klf4 conditional null (Klf4CN) corneal stroma, to further charac...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Young, Robert D., Swamynathan, Shivalingappa K., Boote, Craig, Mann, Mary, Quantock, Andrew J., Piatigorsky, Joram, Funderburgh, James L., Meek, Keith M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761629/
https://ncbi.nlm.nih.gov/pubmed/19387067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-3561
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