p53 Improves Aerobic Exercise Capacity and Augments Skeletal Muscle Mitochondrial DNA Content

RATIONALE: Exercise capacity is a physiological characteristic associated with protection from both cardiovascular and all-cause mortality. p53 regulates mitochondrial function and its deletion markedly diminishes exercise capacity, but the underlying genetic mechanism orchestrating this is unclear....

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Main Authors: Park, Joon-Young, Wang, Ping-yuan, Matsumoto, Takumi, Sung, Ho Joong, Ma, Wenzhe, Choi, Jeong W., Anderson, Stasia A., Leary, Scot C., Balaban, Robert S., Kang, Ju-Gyeong, Hwang, Paul M.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761626/
https://ncbi.nlm.nih.gov/pubmed/19696408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.205310
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