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Nuclear PTHrP targeting regulates PTHrP secretion and enhances LoVo cell growth and survival
Parathyroid hormone-related protein (PTHrP) is expressed by human colon cancer tissue and cell lines; expression correlates with colon carcinoma severity. PTHrP is synthesized as a prepro isoform and contains two targeting sequences – a signal sequence and a nuclear localization signal (NLS). The si...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2761501/ https://ncbi.nlm.nih.gov/pubmed/19616583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.regpep.2009.07.008 |
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