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Chronic Estradiol Replacement Impairs Performance on an Operant Delayed Spatial Alternation Task in Young, Middle-aged, and Old Rats
The current study examined effects of chronic estradiol replacement on a prefrontally-mediated working memory task at different ages in a rodent model. Ovariectomized young, middle-aged, and old Long-Evans rats were given 5% or 10% 17β estradiol in cholesterol vehicle via Silastic implants and teste...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2761498/ https://ncbi.nlm.nih.gov/pubmed/19631212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yhbeh.2009.07.005 |
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