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A role for HDJ-2/HSDJ in correcting subnuclear trafficking, transactivation, and transrepression defects of a glucocorticoid receptor zinc finger mutant.

All steroid receptors possess a bipartite nuclear localization signal sequence (NLS) that localizes within the second zinc finger of their DNA-binding domain. Fine-structure mapping of the rat glucocorticoid receptor (rGS) NLS identified a composite signal composed of three distinct proto-NLSs that...

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Publicat a:Mol Biol Cell
Autors principals: Tang, Y, Ramakrishnan, C, Thomas, J, DeFranco, D B
Format: Artigo
Idioma:Inglês
Publicat: American Society for Cell Biology 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC276130/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9168467/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.8.5.795
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