Interleukin-6 in the bone marrow microenvironment promotes the growth and survival of neuroblastoma cells

Neuroblastoma, the second most common solid tumor in children, frequently metastasizes to the bone marrow and the bone. Neuroblastoma cells present in the bone marrow stimulate the expression of interleukin-6 (IL-6) by bone marrow stromal cells (BMSC) to activate osteoclasts. Here we have examined w...

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Bibliografiske detaljer
Main Authors: Ara, Tasnim, Song, Liping, Shimada, Hiroyuki, Keshelava, Nino, Russell, Heidi V., Metelitsa, Leonid S., Groshen, Susan G., Seeger, Robert C., DeClerck, Yves A.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761219/
https://ncbi.nlm.nih.gov/pubmed/19118018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-0613
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