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Ambrisentan for the treatment of pulmonary arterial hypertension

Ambrisentan is an endothelin receptor antagonist (ERA) that was recently approved for treatment of pulmonary arterial hypertension (PAH). Endothelin (ET) is a potent vasoconstrictor with mitogenic, hypertrophic and pro-inflammatory properties that is upregulated in pulmonary hypertensive diseases. T...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Casserly, Brian, Klinger, James R
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Dove Medical Press 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761178/
https://ncbi.nlm.nih.gov/pubmed/19920913
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