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Kinetics of hallmark biochemical changes in paclitaxel-induced apoptosis

Apoptosis is associated with cascades of biochemical changes, including caspase activation, cleavage of poly-ADP-ribose polymerase (PARP), and fragmentation of genomic DNA. Knowledge of the kinetics of these changes in drug-induced apoptosis is important for designing pharmacodynamic studies. We hav...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Au, Jessie L. S., Wientjes, M. Guill, Kumar, Rajee R., Li, Dong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer-Verlag 1999
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761122/
https://ncbi.nlm.nih.gov/pubmed/11741204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/ps010308
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