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Malignancy in Children with Trisomy 21
Patients with Down syndrome (DS) display a unique spectrum of malignancies, with a 10 to 20-fold increased risk of acute leukemias, and a markedly decreased incidence of solid tumors. This review discusses current understanding of the basis for this distinctive pattern of cancer incidence, and the c...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2761094/ https://ncbi.nlm.nih.gov/pubmed/19176633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2008-0217 |
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