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Immunotoxins for targeted cancer therapy

Immunotoxins are proteins that contain a toxin along with an antibody or growth factor that binds specifically to target cells. Nearly all protein toxins work by enzymatically inhibiting protein synthesis. For the immunotoxin to work, it must bind to and be internalized by the target cells, and the...

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Detalhes bibliográficos
Autor principal: Kreitman, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761061/
https://ncbi.nlm.nih.gov/pubmed/17025272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/aapsj080363
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