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Tissue-specific deletion of the coxsackievirus and adenovirus receptor (CAR) protects mice from virus-induced pancreatitis and myocarditis

In cultured cells, infection by Group B coxsackieviruses (CVB) is mediated by the coxsackievirus and adenovirus receptor (CAR), but the importance of this molecule in CVB disease has not been determined. We used tissue-specific CAR gene deletion to generate mice that lacked CAR within each of two ma...

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Detalhes bibliográficos
Main Authors: Kallewaard, Nicole L., Zhang, Lili, Chen, Jin-Wen, Guttenberg, Marta, Sanchez, Melissa D., Bergelson, Jeffrey M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761025/
https://ncbi.nlm.nih.gov/pubmed/19616768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2009.05.018
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