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The pol3-t Hyperrecombination Phenotype and DNA Damage-Induced Recombination in Saccharomyces cerevisiae Is RAD50 Dependent

The DNA polymerase δ (POL3/CDC2) allele pol3-t of Saccharomyces cerevisiae has previously been shown to be sensitive to methylmethanesulfonate (MMS) and has been proposed to be involved in base excision repair. Our results, however, show that the pol3-t mutation is synergistic for MMS sensitivity wi...

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Autori principali: Galli, Alvaro, Hafer, Kurt, Cervelli, Tiziana, Schiestl, Robert H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761004/
https://ncbi.nlm.nih.gov/pubmed/19834566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2009/312710
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