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Functional interactions between the proline-rich and repeat regions of tau enhance microtubule binding and assembly.

Tau is a neuronal microtubule-associated protein that promotes microtubule assembly, stability, and bundling in axons. Two distinct regions of tau are important for the tau-microtubule interaction, a relatively well-characterized "repeat region" in the carboxyl terminus (containing either three or f...

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Dettagli Bibliografici
Pubblicato in:Mol Biol Cell
Autori principali: Goode, B L, Denis, P E, Panda, D, Radeke, M J, Miller, H P, Wilson, L, Feinstein, S C
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Cell Biology 1997
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC276085/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9190213/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.8.2.353
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