Gene expression in human lupus: bone marrow differentiates active from inactive patients and displays apoptosis and granulopoiesis signatures

OBJECTIVE: The cells of the immune system originate from the bone marrow (BM), where many of them also mature. To better understand the aberrant immune response in systemic lupus erythematosus (SLE), we examined the BM in lupus patients using DNA microarrays and compared it to the peripheral blood (...

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Auteurs principaux: Nakou, Magdalene, Knowlton, Nicholas, Frank, Mark B., Bertsias, George, Osban, Jeanette, Sandel, Clayton E., Papadaki, Eleni, Raptopoulou, Amalia, Sidiropoulos, Prodromos, Kritikos, Heraklis, Tassiulas, Ioannis, Centola, Michael, Boumpas, Dimitrios T.
Format: Artigo
Langue:Inglês
Publié: 2008
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760826/
https://ncbi.nlm.nih.gov/pubmed/18975309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.23961
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