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Overestimation of alternative splicing caused by variable probe characteristics in exon arrays

In higher eukaryotes, alternative splicing is a common mechanism for increasing transcriptome diversity. Affymetrix exon arrays were designed as a tool for monitoring the relative expression levels of hundreds of thousands of known and predicted exons with a view to detecting alternative splicing ev...

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Autors principals: Gaidatzis, Dimos, Jacobeit, Kirsten, Oakeley, Edward J., Stadler, Michael B.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760813/
https://ncbi.nlm.nih.gov/pubmed/19528075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp508
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