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Comparing Artificial Neural Networks, General Linear Models and Support Vector Machines in Building Predictive Models for Small Interfering RNAs

BACKGROUND: Exogenous short interfering RNAs (siRNAs) induce a gene knockdown effect in cells by interacting with naturally occurring RNA processing machinery. However not all siRNAs induce this effect equally. Several heterogeneous kinds of machine learning techniques and feature sets have been app...

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Detalhes bibliográficos
Main Authors: McQuisten, Kyle A., Peek, Andrew S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760777/
https://ncbi.nlm.nih.gov/pubmed/19847297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007522
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