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Adverse experience during early life and adulthood interact to elevate tph2 mRNA expression in serotonergic neurons within the dorsal raphe nucleus

Anxiety disorders, depression and animal models of vulnerability to a depression-like syndrome have been associated with dysregulation of brain serotonergic systems. These effects could result from genetic influences, adverse early life experiences, or acute stressful life events, all of which can a...

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Autores principales: Gardner, Katherine L., Hale, Matthew W., Oldfield, Susan, Lightman, Stafford L., Plotsky, Paul M., Lowry, Christopher A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760611/
https://ncbi.nlm.nih.gov/pubmed/19647049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2009.07.055
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