Targeting of VX2 Rabbit Liver Tumor by Selective Delivery of 3-Bromopyruvate: A Biodistribution and Survival Study

The aim of this study was to determine the biodistribution and tumor targeting ability of (14)C-labeled 3-bromopyruvate ([(14)C]3-BrPA) after i.a. and i.v. delivery in the VX2 rabbit model. In addition, we evaluated the effects of [(14)C]3-BrPA on tumor and healthy tissue glucose metabolism by deter...

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Detalhes bibliográficos
Main Authors: Vali, Mustafa, Vossen, Josephina A., Buijs, Manon, Engles, James M., Liapi, Eleni, Ventura, Veronica Prieto, Khwaja, Afsheen, Acha-Ngwodo, Obele, Shanmugasundaram, Ganapathy, Syed, Labiq, Wahl, Richard L., Geschwind, Jean-Francois H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760588/
https://ncbi.nlm.nih.gov/pubmed/18591216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.141093
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