Epidermal Growth Factor Receptor Pathway Analysis Identifies Amphiregulin as a Key Factor for Cisplatin Resistance of Human Breast Cancer Cells

The use of platinum complexes for the therapy of breast cancer is an emerging new treatment modality. To gain insight into the mechanisms underlying cisplatin resistance in breast cancer, we used estrogen receptor-positive MCF-7 cells as a model system. We generated cisplatin-resistant MCF-7 cells a...

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Autori principali: Eckstein, Niels, Servan, Kati, Girard, Luc, Cai, Di, von Jonquieres, Georg, Jaehde, Ulrich, Kassack, Matthias U., Gazdar, Adi F., Minna, John D., Royer, Hans-Dieter
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760391/
https://ncbi.nlm.nih.gov/pubmed/17942395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M706287200
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