Silencing of Tumor Necrosis Factor Receptor 1 by siRNA in EC109 Cells Affects Cell Proliferation and Apoptosis

Tumor necrosis factor receptor 1 (TNFR1) is a membrane receptor able to bind TNF-α or TNF-β. TNFR1 can suppress apoptosis by activating the NF-κB or JNK/SAPK signal transduction pathway, or it can induce apoptosis through a series of caspase cascade reactions; the particular effect may depend on the...

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Hlavní autoři: Changhui, Ma, Tianzhong, Ma, Zhongjing, Su, Ling, Chen, Ning, Wang, Ningxia, Zhu, Xiancai, Chen, Haibin, Chen
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2009
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760352/
https://ncbi.nlm.nih.gov/pubmed/19826638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2009/760540
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