A glutathione reductase mutant of yeast accumulates high levels of oxidized glutathione and requires thioredoxin for growth.
A glutathione reductase null mutant of Saccharomyces cerevisiae was isolated in a synthetic lethal genetic screen for mutations which confer a requirement for thioredoxin. Yeast mutants that lack glutathione reductase (glr1 delta) accumulate high levels of oxidized glutathione and have a twofold inc...
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| Udgivet i: | Mol Biol Cell |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Cell Biology
1996
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC276027/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8930901/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.7.11.1805 |
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