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Free-Energy Profiles for Ions in the Influenza M(2)-TMD Channel

M(2) transmembrane domain channel (M(2)-TMD) permeation properties are studied using molecular dynamics simulations of M(2)-TMD (1NYJ) embedded in a lipid bilayer (DMPC) with 1 mol/kg NaCl or KCl saline solution. This study allows examination of spontaneous cation and anion entry into the selectivit...

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Bibliografiske detaljer
Main Authors: Mustafa, Morad, Henderson, Douglas J., Busath, David D.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760258/
https://ncbi.nlm.nih.gov/pubmed/19296508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22376
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