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Understanding the pharmacokinetics of Coartem(®)

Artemether and lumefantrine (AL), the active constituents of Coartem(® )exhibit complementary pharmacokinetic profiles. Artemether is absorbed quickly; peak concentrations of artemether and its main active metabolite, dihydroartemisinin (DHA) occur at approximately two hours post-dose, leading to a...

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Detalhes bibliográficos
Main Authors: Djimdé, Abdoulaye, Lefèvre, Gilbert
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760239/
https://ncbi.nlm.nih.gov/pubmed/19818171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-8-S1-S4
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