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Facilitating effects of berberine on rat pancreatic islets through modulating hepatic nuclear factor 4 alpha expression and glucokinase activity

AIM: To observe the effect of berberine on insulin secretion in rat pancreatic islets and to explore its possible molecular mechanism. METHODS: Primary rat islets were isolated from male Sprague-Dawley rats by collagenase digestion and treated with different concentrations (1, 3, 10 and 30 μmol/L) o...

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Autors principals: Wang, Zhi-Quan, Lu, Fu-Er, Leng, San-Hua, Fang, Xin-Sheng, Chen, Guang, Wang, Zeng-Si, Dong, Li-Ping, Yan, Zhong-Qing
Format: Artigo
Idioma:Inglês
Publicat: The WJG Press and Baishideng 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760199/
https://ncbi.nlm.nih.gov/pubmed/18932278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.14.6004
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