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Perforation of the colon by invading recurrent gastrointestinal stromal tumors during sunitinib treatment

The molecular targets of sunitinib are receptor tyrosine kinases (RTKs), and this drug has also been known to exert blocking effects on the activation of KIT, which is similar to the mechanism of action of imatinib. Moreover, sunitinib has an additional anti-angiogenic effect through its inhibition...

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Detalhes bibliográficos
Main Authors: Hur, Hoon, Park, Ae Ryoung, Jee, Sung Bae, Jung, Seung Eun, Kim, Wook, Jeon, Hae Myung
Formato: Artigo
Idioma:Inglês
Publicado em: The WJG Press and Baishideng 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760196/
https://ncbi.nlm.nih.gov/pubmed/18932293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.14.6096
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