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Perforation of the colon by invading recurrent gastrointestinal stromal tumors during sunitinib treatment

The molecular targets of sunitinib are receptor tyrosine kinases (RTKs), and this drug has also been known to exert blocking effects on the activation of KIT, which is similar to the mechanism of action of imatinib. Moreover, sunitinib has an additional anti-angiogenic effect through its inhibition...

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Autors principals: Hur, Hoon, Park, Ae Ryoung, Jee, Sung Bae, Jung, Seung Eun, Kim, Wook, Jeon, Hae Myung
Format: Artigo
Idioma:Inglês
Publicat: The WJG Press and Baishideng 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760196/
https://ncbi.nlm.nih.gov/pubmed/18932293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.14.6096
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