Evolutionary Dynamics of Human Rotaviruses: Balancing Reassortment with Preferred Genome Constellations

Group A human rotaviruses (RVs) are a major cause of severe gastroenteritis in infants and young children. Yet, aside from the genes encoding serotype antigens (VP7; G-type and VP4; P-type), little is known about the genetic make-up of emerging and endemic human RV strains. To gain insight into the...

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Main Authors: McDonald, Sarah M., Matthijnssens, Jelle, McAllen, John K., Hine, Erin, Overton, Larry, Wang, Shiliang, Lemey, Philippe, Zeller, Mark, Van Ranst, Marc, Spiro, David J., Patton, John T.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2009
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760143/
https://ncbi.nlm.nih.gov/pubmed/19851457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000634
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