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Variants in Doublecortin- and Calmodulin Kinase Like 1, a Gene Up-Regulated by BDNF, Are Associated with Memory and General Cognitive Abilities

BACKGROUND: Human memory and general cognitive abilities are complex functions of high heritability and wide variability in the population. The brain-derived neurotrophic factor (BDNF) plays an important role in mammalian memory formation. METHODOLOGY / PRINCIPAL FINDING: Based on the identification...

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Detalhes bibliográficos
Main Authors: Le Hellard, Stéphanie, Håvik, Bjarte, Espeseth, Thomas, Breilid, Harald, Løvlie, Roger, Luciano, Michelle, Gow, Alan J., Harris, Sarah E., Starr, John M., Wibrand, Karin, Lundervold, Astri J., Porteous, David J., Bramham, Clive R., Deary, Ian J., Reinvang, Ivar, Steen, Vidar M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760101/
https://ncbi.nlm.nih.gov/pubmed/19844571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007534
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