Photochemical control of endogenous ion channels and cellular excitability

Light-activated ion channels provide a precise and non-invasive optical means for controlling action potential firing, but the genes encoding these channels must first be delivered and expressed in target cells. Here we describe a method for bestowing light sensitivity onto endogenous ion channels t...

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Bibliographic Details
Main Authors: Fortin, Doris L., Banghart, Matthew R., Dunn, Timothy W., Borges, Katharine, Wagenaar, Daniel A., Gaudry, Quentin, Karakossian, Movses H., Otis, Thomas S., Kristan, William B., Trauner, Dirk, Kramer, Richard H.
Format: Artigo
Language:Inglês
Published: 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760097/
https://ncbi.nlm.nih.gov/pubmed/18311146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1187
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