The small GTP-binding proteins, Rac and Rho, regulate cytoskeletal organization and exocytosis in mast cells by parallel pathways.

In mast cells, activation of GTP-binding proteins induces centripetal reorganization of actin filaments. This effect is due to disassembly, relocalization, and polymerization of F-actin and is dependent on two small GTPases, Rac and Rho. Activities of Rac and Rho are also essential for the secretory...

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Pubblicato in:	Mol Biol Cell
Autori principali:	Norman, J C, Price, L S, Ridley, A J, Koffer, A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Cell Biology 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275992/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8885237/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.7.9.1429
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