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Selective activation of tumor growth-promoting Ca(2+ )channel MS4A12 in colon cancer by caudal type homeobox transcription factor CDX2

Colon cancer-associated MS4A12 is a novel colon-specific component of store-operated Ca(2+ )(SOC) entry sensitizing cells for epidermal growth factor (EGF)-mediated effects on proliferation and chemotaxis. In the present study, we investigated regulation of the MS4A12 promoter to understand the mech...

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Détails bibliographiques
Auteurs principaux: Koslowski, Michael, Türeci, Özlem, Huber, Christoph, Sahin, Ugur
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759907/
https://ncbi.nlm.nih.gov/pubmed/19781065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-8-77
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