Importance of replication in microarray gene expression studies: Statistical methods and evidence from repetitive cDNA hybridizations

We present statistical methods for analyzing replicated cDNA microarray expression data and report the results of a controlled experiment. The study was conducted to investigate inherent variability in gene expression data and the extent to which replication in an experiment produces more consistent...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Lee, Mei-Ling Ting, Kuo, Frank C., Whitmore, G. A., Sklar, Jeffrey
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 2000
Témata:	Physical Sciences
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC27599/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10963655/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.18.9834
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