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Immunogenicity and Antitumor Effects of Vaccination with Peptide Vaccine +/− GM-CSF and/or Interferon α2b in Advanced Metastatic Melanoma: the ECOG Phase II Trial E1696

PURPOSE: No therapy has ever demonstrated prolongation of survival in stage IV metastatic melanoma. The association of cytokine-induced autoimmunity with improved prognosis led us to investigate the impact of multi-epitope melanoma vaccines alone and in combination with cytokines in this Eastern Coo...

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Detalhes bibliográficos
Main Authors: Kirkwood, John M., Lee, Sandra, Moschos, Stergios J., Albertini, Mark R., Michalak, John C., Sander, Cindy, Whiteside, Theresa, Butterfield, Lisa H., Weiner, Louis
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759898/
https://ncbi.nlm.nih.gov/pubmed/19228745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-1231
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